NASH-NAFLD management

Management of a disease must be informed by under- standing of its natural history and prognosis, diagnostic criteria and methods, and by our knowledge of treat- ments available and their efficacy. It is the purpose of this contribution to draw aspects of all three areas together so that we propose the best management guide- lines and strategy in the light of present knowledge towards the end of 2002. Non-alcoholic fatty liver disease (NAFLD) is largely encountered in office and outpatient practice (1) most patients have either no relevant symptoms or these are ill defined at presentation - these facts inform our manage- ment decisions.